Normally, allergens are harmless. But when a person has allergies, the body thinks these allergens are harmful. The body then attacks allergens with antibodies called immunoglobulin E (IgE). These antibodies are attached to special cells called mast cells. Allergens stick to the antibodies. This makes the mast cells release histamine and other chemicals causing an allergic reaction. When the chemicals irritate nearby nasal tissue, this causes nasal allergy symptoms. When this happens in the lungs' breathing tubes, it can cause asthma symptoms such as cough and wheeze. When the reaction involves the whole body, this can be a severe allergic reaction. An allergic reaction can happen anywhere in the body. This includes the skin, eyes, lining of the stomach, nose, sinuses, throat, and lungs. These are the places where immune system cells are found to fight off germs that are breathed in, swallowed, or come in contact with the skin.
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